Pseudotumor of hemophilia in a patient with PTC deficiency.

LTHOUGH the hemarthroses of hemophilia are well-known manifestations of this disease, it is not commonly realized that abnormal bleeding may also cause bone destruction in sites remote from the articulations. Such osteolytic lesions are generally accompanied by massive soft tissue swelling and usually, therefore, are called pseudotumors of hemophilia. The clinical and roentgenologic manifestations may be indistinguishable from those of malignant osteolytic tumors. A total of only 18 such cases have been recorded in the literature. This rare but serious complication is illustrated in the following case report of a patient with PTC deficiency.